Cannon & Nedergaard 2012 in Nature

Hi! My personal, original plan was to have a new post every week, but I am already behind.
*face palm*
But you know what they say "sometimes plan change", I thinkkkk.
*scratches head*
Anyways, I'm going to squeeze out this post, because I was behind last week.

I'm pretty excited about this short, simple review that presented much to think about from Drs. Barbara Cannon and Jan Nedergaard, both from the Wenner-Gren Institute of Stockholm University.

Dr. Barbara Cannon

Dr. Jan Nedergaard

1. Citation:

Cannon B & Nedergaard J (2012). Neither brown nor white. Nature 286(488):286-287. 

2. Purpose:  

The purpose of this review is to provide a brief introduction about the beige/brite fat cells based on different works from other researchers. In the review, Drs. Cannon and Nedergaard specifically referred to the work of Wu et al [Wu J et al (2012).Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell 150(2): 366-376.]
as providing convincing evidence for the new type of fat cells. 

3. Data presentation: 

They included a concept figure demonstrating the differences between classical brown, classical white, and the new beige fat cells. 

 4. Conclusions:
"The identification of a third type of fat cell in mice and humans might open up new avenues for combating obesity."

Drs. Cannon and Nedergaard raised many good points to consider:

"These results raise several questions. What is the origin of the two types of cell? Are there
two distinct types of pericytes (cells that are wrapped along the blood capillaries and supposedly give rise to fat cells)? Or does one cell type derive, for example, from the bone marrow? How can certain white-like adipocytes, which in general possess very few mitochondria, suddenly enhance their mitochondrial complement during the ‘beiging/britening’ process?" 

5. Novelty:
I felt that the novelty of this review lies in the thought provoking questions they provided in the conclusion of what this beige cell can mean for human treatment of obesity. 

6. Future directions: and 7. Money line: 

Hahaha, from my perspective, I still think it's questions that I previously mentioned in the conclusions and novelty parts.